Lonely pet chameleon Rango (voice of Johnny Depp) gets separated from his owners and lands in a desert town. Once in the wild, Rango teams up with a spunky frontier girl (Isla Fisher) and takes on a villainous rattlesnake (Bill Nighy). While Depp turns his bug-eyed reptile into a charismatic character, the plot gets lost in a maze of tangents and the story has too many tasteless jokes — like a prostate gag — that are not kid-friendly.
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